NFL Predictions

Tennessee Titans vs San Francisco 49ers

Sunday, December 14, 2025 at 4:25pm EST

Away

Tennessee Titans

Spread +12.5

Home

Spread -12.5

49%

51%

Spread Tennessee Titans +12.5 San Francisco 49ers -12.5

Moneyline Tennessee Titans +625 San Francisco 49ers -950

Total Over 44.5 (-108) Under 44.5 (-112)

Professional Picks

3 listed

Tom Strickland Total pick

In Progress

Simon Says Total pick

In Progress

Matt O'Brien Spread pick

In Progress