NCAAF Predictions

Clemson Tigers vs Louisville Cardinals

Friday, November 14, 2025 at 7:30pm EST

Away

Clemson Tigers

Spread +2.5

Home

Spread -2.5

48%

52%

Spread Clemson Tigers +2.5 Louisville Cardinals -2.5

Moneyline Clemson Tigers +110 Louisville Cardinals -130

Total Over 50.5 (-110) Under 50.5 (-110)

Professional Picks

5 listed

Tom Strickland Spread pick

In Progress

Tom Strickland Total pick

In Progress

Simon Says Total pick

In Progress

Wes Salvato Spread pick

In Progress

Wes Salvato Total pick

In Progress