NFL Predictions

San Francisco 49ers vs Houston Texans

Sunday, October 26, 2025 at 1:00pm EST

Away

San Francisco 49ers

Spread +3.5

Home

Spread -3.5

61%

39%

Spread San Francisco 49ers +3.5 Houston Texans -3.5

Moneyline San Francisco 49ers +140 Houston Texans -165

Total Over 41.5 (+100) Under 41.5 (-120)

Professional Picks

3 listed

Tom Strickland Spread pick

In Progress

Tom Strickland Total pick

In Progress

Wes Salvato Spread pick

In Progress